One of a few serial killers that were never found, depicted in the 2007 movie "Zodiac" starring Jake Gyllenhaal.
The Zodiac Killer is a serial killer who operated in Northern California in the late 1960s. His identity remains unknown. The Zodiac coined his name in a series of taunting letters he sent to the press. His letters included four cryptograms (or ciphers), three of which have yet to be solved.
The Zodiac murdered five known victims in Benicia, Vallejo, Lake Berryessa, and San Francisco between December 1968 and October 1969. Four men and three women between the ages of 16 and 29 were targeted. Others have also been suspected to be Zodiac victims, albeit inconclusively. The lack of consensus about the number of victims, the inability of law enforcement to crack the ciphers, and the fact that several people have inconclusively been portrayed as "persons of interest" or possible suspects, has elicited this case's designation as a perfect crime.
In April 2004, the San Francisco Police Department marked the case "inactive", but reopened it some time before March 2007. The case remains open in other jurisdictions as well.
Source: Wikipedia
SACRAMENTO (CBS13) ? 
The Zodiac Killer attacked at least eight people, terrorizing the Bay Area and taunting police in the 60's and 70's. Thursday, the FBI confirmed to CBS13 they are now running laboratory tests on some items that may link a suspect to the killer.
Read more at CBS 13 Sacramento, California
Story link courtesy of:
http://cbs13.com/crime/zodiac.killer.kaufman.2.805799.html